This paper discusses a new method by which the boundaries of the objects of the angiography can be located with recursive regularization filter and wavelet transform.The edges of the vessel can be accurately abstracted by the wavelet transform,after the noise and objects that fall below a scale of interest have been selectively removed by the filter under the regularization extent chosen.The result in this paper has explicitly show that it provides adequately accurate boundaries of the vessel that are of sufficient size in the width regularization extent.Comparing the method directly using wavelet transform and regularization filter respectively with the method which we proposed,the advantage of the method describing in this paper is complementary to the default that the wavelet transform badly reduces the correlative noise and add the multiresolution analysis which the regularization filter do not share.